NeoMass AAAC is used with Tandem Mass Spectrometry to detect concentrations of amino acid, free carnitine, acylcarnitines, succinylacetone and argininosuccinic acid.
Features
- The broadest available panel of analytes
- Easy sample preparation without derivatization
- More Analytes with less expenses
- Possibility of Automatic Sample Preparation
- 3 levels of blood spots controls – Low, Mid, High
- Unique endogenous level control
- Unraveling of Proximal & Distal Urea Cycle Disorder
- Includes Succinylacetone (SUAC) and Argininosuccinic Acid (ASA) standards
- Assay for screening more than 50 inherited metabolic disorders
Specification
- Ready-to-use kit for 960 tests
- 4 of steps: Punch, Extraction, Transfer, Injection into MS/MS
- Sample extraction without derivatization
- 4 sets of Isotope labelled internal Standards: 15 Amino Acids + 13 (Acyl) Carnitines + SUAC (Tyrosemia type-1) + ASA (Argininosuccinic Acidemia)
3 Dried Blood Spot Controls framing the decisional cut-off area for each of the matching internal standards - Turnaround time for 96 samples approximately 3 hours
- High specificity and sensitivity by MS/MS detection
- Validation for multiple instrument applications
- Final concentrations calculated based on accurate peak area ratios
- compared to only peak intensities ratios